Journal Article Proteins Research Support, Non-U.S. Gov't Conformational sampling Cysteine K848JZ4886 Nullspace Protein Protein collective motions Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Rigidity Singular configuration collision-avoidance computational biology conformational dynamics cryo-temperature cysteine modification enzyme conformational dynamics high dimensional motion and path planning inverse kinematics molecular dynamics simulations molecular rigidity poisson sampling radiation damage radiation-controlled photo-oxidation room temperature serial X-ray crystallography