Journal Article Research Support, Non-U.S. Gov't acumulación de mutaciones balancing selection depresión endogámica diversidad genética extinction vortex genetic diversity inbreeding depression interaction diversity hypothesis mathematical model mutation accumulation phytochemical diversity plant–herbivore interactions screening hypothesis selección estabilizadora synergy hypothesis vórtice de extinción 平衡选择 灭绝漩涡 突变积累 近交衰退 遗传多样性