AICDA (Activation-Induced Cytidine Deaminase) AID APOBEC1 Activation-induced cytidine deaminase CSR Case Reports Cytidine Deaminase EC 3.5.4.- EC 3.5.4.5 GC Hyper-immunoglobulin M Journal Article Mutation NES NLS PI Research Support, Non-U.S. Gov't SHM activation-induced cytidine deaminase apolipoprotein B mRNA editing catalytic polypeptide 1 class switch recombination gene conversion hAID human AID nuclear export signal nuclear localization signal propidium iodide somatic hypermutation wild type wt