Role of Like Heterochromatin Protein1 (LHP1) in the root apical meristem and stem cell niche maintenance in Arabidopsis
Copyright © 2025 Elsevier B.V. All rights reserved.
| Veröffentlicht in: | Plant science : an international journal of experimental plant biology. - 1985. - 362(2025) vom: 03. Sept., Seite 112740 |
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| 1. Verfasser: | |
| Weitere Verfasser: | , , , , , , , , |
| Format: | Online-Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2025
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| Zugriff auf das übergeordnete Werk: | Plant science : an international journal of experimental plant biology |
| Schlagworte: | Journal Article Arabidopsis Auxin CLF Epigenetics LHP1 PcG Root stem cell niche |
| Zusammenfassung: | Copyright © 2025 Elsevier B.V. All rights reserved. Epigenetic regulation by Polycomb Group (PcG) is essential for controlling gene repression. In plants, PcG is involved in all developmental processes, from embryogenesis to floral development, including root development. LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) has been described as a PcG component, capable of recognizing the H3K27me3 mark, that together with CLF, a PcG histone methyltransferase, represses gene expression. Here, we provide evidence that LHP1 plays different roles in the root apical meristem: a canonical role to repress gene expression in a similar way to CLF, and another where it participates in transcriptional activation, revealing a dual regulation of LHP1 that is tissue-specific. We also found novel roles for LHP1 in maintaining the root stem cell niche (RSCN), regulating columella stem cell (CSC) differentiation, auxin signaling and perception of light and gravitropic signals. Our findings integrate a novel epigenetic component into the regulatory network that maintains homeostasis of the RSCN |
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| Beschreibung: | Date Revised 07.09.2025 published: Print-Electronic Citation Status Publisher |
| ISSN: | 1873-2259 |
| DOI: | 10.1016/j.plantsci.2025.112740 |