High-Density Inverted Micellar Intermediates Promote Membrane Fusion of Cationic Liposomes in Drug Delivery

Liposomes have become increasingly popular as carriers for pharmaceutically relevant molecules such as nucleic acids, proteins, or anticancer drugs. The bottleneck in delivering such vehicles is their inefficient endosomal uptake by target cells. To bypass endosomal degradation and enhance delivery...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 41(2025), 29 vom: 29. Juli, Seite 19055-19070
1. Verfasser: Kolašinac, Rejhana (VerfasserIn)
Weitere Verfasser: Strandberg, Erik, Schmitt, Laura Maria, Jaksch, Sebastian, Berkamp, Sabrina, Dreissen, Georg, Qdemat, Asma, Förster, Stephan, Sachse, Carsten, Ulrich, Anne S, Merkel, Rudolf, Csiszár, Agnes
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2025
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article 2D/3D phase transition cationic liposomes drug delivery interlamellar attachments (ILA) inverted micellar fusion-intermediates (IMI) membrane fusion Liposomes Micelles Cations