Engineered Living Systems Based on Gelatin Design, Manufacturing, and Applications

Engineered Living Systems Based on Gelatin : Design, Manufacturing, and Applications

© 2025 Wiley‐VCH GmbH.

Détails bibliographiques
Publié dans:Advanced materials (Deerfield Beach, Fla.). - 1998. - (2025) vom: 05. Feb., Seite e2416260
Auteur principal: Wang, Zhenwu (Auteur)
Autres auteurs: Lin, Zeng, Mei, Xuan, Cai, Ling, Lin, Ko-Chih, Rodríguez, Jimena Flores, Ye, Zixin, Parraguez, Ximena Salazar, Guajardo, Emilio Mireles, García Luna, Pedro Cortés, Zhang, Jun Yi Joey, Zhang, Yu Shrike
Format: Article en ligne
Langue:English
Publié: 2025
Accès à la collection:Advanced materials (Deerfield Beach, Fla.)
Sujets:Journal Article Review 3D printing biofabrication engineered living systems gelatin hydrogels
Description
Résumé:© 2025 Wiley‐VCH GmbH.
Engineered living systems (ELSs) represent purpose-driven assemblies of living components, encompassing cells, biomaterials, and active agents, intricately designed to fulfill diverse biomedical applications. Gelatin and its derivatives have been used extensively in ELSs owing to their mature translational pathways, favorable biological properties, and adjustable physicochemical characteristics. This review explores the intersection of gelatin and its derivatives with fabrication techniques, offering a comprehensive examination of their synergistic potential in creating ELSs for various applications in biomedicine. It offers a deep dive into gelatin, including its structures and production, sources, processing, and properties. Additionally, the review explores various fabrication techniques employing gelatin and its derivatives, including generic fabrication techniques, microfluidics, and various 3D printing methods. Furthermore, it discusses the applications of ELSs based on gelatin in regenerative engineering as well as in cell therapies, bioadhesives, biorobots, and biosensors. Future directions and challenges in gelatin fabrication are also examined, highlighting emerging trends and potential areas for improvements and innovations. In summary, this comprehensive review underscores the significance of gelatin-based ELSs in advancing biomedical engineering and lays the groundwork for guiding future research and developments within the field
Description:Date Revised 19.03.2025
published: Print-Electronic
Citation Status Publisher
ISSN:1521-4095
DOI:10.1002/adma.202416260