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241126s2024 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.4c02764
|2 doi
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|a eng
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|a Yuqing, Fnu
|e verfasserin
|4 aut
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|a Durable Antimicrobial Microstructure Surface (DAMS) Enabled by 3D-Printing and ZnO Nanoflowers
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|c 2024
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|a Text
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|a Date Revised 03.12.2024
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|a published: Print-Electronic
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|a UpdateOf: bioRxiv. 2024 Jun 14:2024.06.11.598554. doi: 10.1101/2024.06.11.598554. - PMID 38915492
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|a Citation Status Publisher
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|a Numerous studies have been trying to create nanomaterial-based antimicrobial surfaces to prevent infections due to bacterial growth. One major challenge in real-world applications of these surfaces is their mechanical durability. In this study, we introduce durable antimicrobial microstructure surface (DAMS), which integrates DLP 3D-printed microstructures with zinc oxide (ZnO) nanoflowers. The microstructures function as protection armor for the nanoflowers during abrasion. The antimicrobial ability was evaluated by immersing in 2E8 CFU/mL Escherichia coli (E. coli) suspension and then evaluated using electron microscopy. Our results indicated that DAMS reduced bacterial coverage by more than 90% after 12 h of incubation and approximately 50% after 48 h of incubation before abrasion. More importantly, bacterial coverage was reduced by approximately 50% after 2 min of abrasion with a tribometer, and DAMS remains effective even after 6 min of abrasion. These findings highlight the potential of DAMS as an affordable, scalable, and durable antimicrobial surface for various biomedical applications
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|a Journal Article
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|a Zhang, Shuhuan
|e verfasserin
|4 aut
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|a Peng, Ruonan
|e verfasserin
|4 aut
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|a Silva, Justin
|e verfasserin
|4 aut
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|a Ernst, Olivia
|e verfasserin
|4 aut
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|a Lapizco-Encinas, Blanca H
|e verfasserin
|4 aut
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|a Liu, Rui
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|a Du, Ke
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
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|u http://dx.doi.org/10.1021/acs.langmuir.4c02764
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