A comparative study of two-sample tests for interval-censored data

Interval-censored data are ubiquitous in clinical studies where actual time-to-event is difficult to measure. A number of nonparametric tests have been proposed to conduct a two-sample test using interval-censored data, and these tests can be used for assessing and comparing treatment effects over t...

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Détails bibliographiques
Publié dans:Journal of statistical computation and simulation. - 1999. - 91(2021), 18 vom: 20., Seite 3894-3916
Auteur principal: Hu, Linhan (Auteur)
Autres auteurs: Mandal, Soutrik, Sinha, Samiran
Format: Article en ligne
Langue:English
Publié: 2021
Accès à la collection:Journal of statistical computation and simulation
Sujets:Journal Article Generalized log-rank test Turnbull’s algorithm interval-censored likelihood ratio test multiple imputation score test
Description
Résumé:Interval-censored data are ubiquitous in clinical studies where actual time-to-event is difficult to measure. A number of nonparametric tests have been proposed to conduct a two-sample test using interval-censored data, and these tests can be used for assessing and comparing treatment effects over the control group. Alternatively, as commonly perceived, parametric tests can also be used assuming data are generated from a parametric family of distributions. To provide some guidance on choosing an appropriate method, in this paper, the performance of parametric tests and a series of nonparametric tests are compared through extensive simulation studies that cover a wide range of scenarios with varying sample sizes, varying censoring mechanisms and varying alternative hypotheses. For the purpose of illustration, we also apply these procedures to analyse three real datasets
Description:Date Revised 31.07.2024
published: Print-Electronic
Citation Status PubMed-not-MEDLINE
ISSN:0094-9655
DOI:10.1080/00949655.2021.1955884