Phosphatidylglycerol Acts as a Switch for Cholesterol-Dependent Membrane Binding of ApoE Signal Peptide

The apolipoprotein E (ApoE) signal peptide is a short stretch of N-terminal amino acids that direct the ApoE protein to the endoplasmic reticulum after synthesis. Previous studies have shown that this peptide can bind to lipid membranes in a cholesterol-dependent manner; however, the mechanism of th...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 40(2024), 15 vom: 16. Apr., Seite 8126-8132
1. Verfasser: Pradhan, Sasmita (VerfasserIn)
Weitere Verfasser: Mirdha, Lipika, Sengupta, Tanusree, Chakraborty, Hirak
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Protein Sorting Signals Phosphatidylglycerols Apolipoproteins E Cholesterol 97C5T2UQ7J Peptides