Preserving DNA in Biodegradable Organosilica Encapsulates

A core-shell strategy was developed to protect synthetic DNA in organosilica particles encompassing dithiol linkages allowing for a DNA loading of 1.1 wt %. DNA stability tests involving bleach as an oxidant showed that following the procedure DNA was sandwiched between core particles of ca. 450 nm...

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Détails bibliographiques
Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 38(2022), 37 vom: 20. Sept., Seite 11191-11198
Auteur principal: Koch, Julian (Auteur)
Autres auteurs: Kerl, Ann-Christin, Schawalder, Natascha, Luescher, Anne M, Nguyen, Bichlien H, Strauss, Karin, Stark, Wendelin J, Grass, Robert N
Format: Article en ligne
Langue:English
Publié: 2022
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, Non-U.S. Gov't Oxidants Reducing Agents Toluene 3FPU23BG52 Silicon Dioxide 7631-86-9 DNA 9007-49-2 plus... Glutathione GAN16C9B8O dithiol U89B11P7SC