Retroperitoneal abscess and splenitis with Clostridium spp. in a dog
© 2022 American Society for Veterinary Clinical Pathology.
| Publié dans: | Veterinary clinical pathology. - 1975. - 51(2022), 4 vom: 15. Dez., Seite 560-564 |
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| Auteur principal: | |
| Autres auteurs: | , , |
| Format: | Article en ligne |
| Langue: | English |
| Publié: |
2022
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| Accès à la collection: | Veterinary clinical pathology |
| Sujets: | Case Reports Journal Article bacteriology culture gram-positive endospore-forming rods mass spectrometry microbiology |
| Résumé: | © 2022 American Society for Veterinary Clinical Pathology. An 11-year-old spayed female Basset Hound was presented to the Colorado State University Veterinary Teaching Hospital for evaluation of a 7-week history of intermittent collapse, waxing and waning lethargy, and hyporexia. Abdominal ultrasound revealed a 6-mm hypoechoic splenic nodule that, on cytologic evaluation, revealed marked neutrophilic inflammation with intracellular and extracellular bacterial rods frequently producing oval subterminal to terminal endospores, suggestive of Clostridium. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF) performed on bacteria isolated from this nodule initially identified a Clostridium species, which was eventually confirmed with 16 s rDNA sequencing. Computed tomography (CT) and exploratory laparotomy subsequently identified a 2.5-cm diameter tubular structure beginning at the caudal aspect of the right kidney and coursing caudally containing gas and fluid, consistent with a retroperitoneal abscess, which was resected and also cultured Clostridium spp. The dog was discharged 3 days postoperatively and was alive at the time of writing, 7 months after discharge. This case highlights a previously unrecognized bacterial agent in a retroperitoneal abscess. The use of cytologic evaluation yielded a diagnosis of endospore-forming bacteria suggestive of Clostridium sooner than culture and histopathology, which allowed for adjustment in the antibiotic protocol |
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| Description: | Date Completed 02.12.2022 Date Revised 02.12.2022 published: Print-Electronic Citation Status MEDLINE |
| ISSN: | 1939-165X |
| DOI: | 10.1111/vcp.13112 |