Evaluation of Blood Induced Influence for High-Definition Intravascular Ultrasound (HD-IVUS)

High-definition intravascular ultrasound (HD-IVUS) utilizing more than 80 MHz frequency to assess atherosclerotic plaque, can theoretically achieve an axial resolution of less than [Formula: see text]. However, the blood is a high-attenuation source at high frequency, which would affect the imaging...

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Publié dans:IEEE transactions on ultrasonics, ferroelectrics, and frequency control. - 1986. - 69(2022), 1 vom: 01. Jan., Seite 98-105
Auteur principal: Liang, Suzi (Auteur)
Autres auteurs: Su, Min, Liu, Baoqiang, Liu, Rong, Zheng, Hairong, Qiu, Weibao, Zhang, Zhiqiang
Format: Article en ligne
Langue:English
Publié: 2022
Accès à la collection:IEEE transactions on ultrasonics, ferroelectrics, and frequency control
Sujets:Journal Article Research Support, Non-U.S. Gov't
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520 |a High-definition intravascular ultrasound (HD-IVUS) utilizing more than 80 MHz frequency to assess atherosclerotic plaque, can theoretically achieve an axial resolution of less than [Formula: see text]. However, the blood is a high-attenuation source at high frequency, which would affect the imaging quality. There has been no research evaluating the blood-induced influence on HD-IVUS imaging. And whether a temporary removal of blood is needed for HD-IVUS is unknown. In this study, an ultrahigh-frequency (100 MHz) ultrasound transducer was developed to evaluate the blood-induced attenuation for HD-IVUS imaging. A series of tungsten-wire phantom images in saline and blood at varying hematocrits were obtained. The images showed that blood did influence the ultrahigh-frequency imaging quality greatly. The signal-to-noise ratio (SNR) decrease by 71.7% in porcine whole blood compared to that in saline at the same depth of 2.3 mm. Moreover, the potential flushing schemes for HD-IVUS were studied in varying hematocrits. Three flushing agents commonly used in intravascular optical coherence tomography (IV-OCT) were investigated, including iohexol, mannitol, and dextran 5% and saline as the control group. The attenuation of blood in varying hematocrits/flushing agents was measured from 90 to 110 MHz. The result indicated dextran 5% was a suitable flushing agent for HD-IVUS due to its less signal attenuation compared to others 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
700 1 |a Su, Min  |e verfasserin  |4 aut 
700 1 |a Liu, Baoqiang  |e verfasserin  |4 aut 
700 1 |a Liu, Rong  |e verfasserin  |4 aut 
700 1 |a Zheng, Hairong  |e verfasserin  |4 aut 
700 1 |a Qiu, Weibao  |e verfasserin  |4 aut 
700 1 |a Zhang, Zhiqiang  |e verfasserin  |4 aut 
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