Adsorption of a Humanized Monoclonal Antibody onto Thermoresponsive Copolymer-Grafted Sepharose Fast Flow Sorbents

The batch adsorption behavior of a humanized monoclonal antibody (hIgG2 mAb) with thermoresponsive polymer (TRP)-modified Sepharose Fast Flow sorbents with different compositions of grafted copolymers is described. At high protein loadings, the adsorption with negatively charged copolymer-modified s...

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Veröffentlicht in:	Langmuir : the ACS journal of surfaces and colloids. - 1985. - 37(2021), 3 vom: 26. Jan., Seite 1054-1061
1. Verfasser:	Tan, Sinuo (VerfasserIn)
Weitere Verfasser:	Saito, Kei, Hearn, Milton T W
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2021
Zugriff auf das übergeordnete Werk:	Langmuir : the ACS journal of surfaces and colloids
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Antibodies, Monoclonal Polymers Sepharose 9012-36-6