How Do Surface Properties of Nanoparticles Influence Their Diffusion in the Extracellular Matrix? A Model Study in Matrigel Using Polymer-Grafted Nanoparticles

Diffusion of nanomedicines inside the extracellular matrix (ECM) has been identified as a key factor to achieve homogeneous distribution and therefore therapeutic efficacy. Here, we sought to determine the impact of nanoparticles' (NPs) surface properties on their ability to diffuse in the ECM....

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Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 36(2020), 35 vom: 08. Sept., Seite 10460-10470
Auteur principal: Le Goas, Marine (Auteur)
Autres auteurs: Testard, Fabienne, Taché, Olivier, Debou, Nabila, Cambien, Béatrice, Carrot, Geraldine, Renault, Jean-Philippe
Format: Article en ligne
Langue:English
Publié: 2020
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Drug Combinations Laminin Polymers Proteoglycans matrigel 119978-18-6 Gold plus... 7440-57-5 Collagen 9007-34-5