Formation of Ligand Clusters on Multimodal Chromatographic Surfaces

Multimodal chromatography is a powerful tool which uses multiple modes of interaction, such as charge and hydrophobicity, to purify protein-based therapeutics. In this work, we performed molecular dynamics simulations of a series of multimodal cation-exchange ligands immobilized on a hydrophilic sel...

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Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 35(2019), 51 vom: 24. Dez., Seite 16770-16779
Auteur principal: Bilodeau, Camille L (Auteur)
Autres auteurs: Lau, Edmond Y, Roush, David, Garde, Shekhar, Cramer, Steven M
Format: Article en ligne
Langue:English
Publié: 2019
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.