The Macromolecular Femtosecond Crystallography Instrument at the Linac Coherent Light Source

The Macromolecular Femtosecond Crystallography Instrument at the Linac Coherent Light Source

open access.

Détails bibliographiques
Publié dans:Journal of synchrotron radiation. - 1994. - 26(2019), Pt 2 vom: 01. März, Seite 346-357
Auteur principal: Sierra, Raymond G (Auteur)
Autres auteurs: Batyuk, Alexander, Sun, Zhibin, Aquila, Andrew, Hunter, Mark S, Lane, Thomas J, Liang, Mengning, Yoon, Chun Hong, Alonso-Mori, Roberto, Armenta, Rebecca, Castagna, Jean Charles, Hollenbeck, Michael, Osier, Ted O, Hayes, Matt, Aldrich, Jeff, Curtis, Robin, Koglin, Jason E, Rendahl, Theodore, Rodriguez, Evan, Carbajo, Sergio, Guillet, Serge, Paul, Rob, Hart, Philip, Nakahara, Kazutaka, Carini, Gabriella, DeMirci, Hasan, Dao, E Han, Hayes, Brandon M, Rao, Yashas P, Chollet, Matthieu, Feng, Yiping, Fuller, Franklin D, Kupitz, Christopher, Sato, Takahiro, Seaberg, Matthew H, Song, Sanghoon, van Driel, Tim B, Yavas, Hasan, Zhu, Diling, Cohen, Aina E, Wakatsuki, Soichi, Boutet, Sébastien
Format: Article en ligne
Langue:English
Publié: 2019
Accès à la collection:Journal of synchrotron radiation
Sujets:Journal Article X-ray FEL X-ray free-electron laser protein crystallography room-temperature crystallography serial femtosecond crystallography time-resolved crystallography
Description
Résumé:open access.
The Macromolecular Femtosecond Crystallography (MFX) instrument at the Linac Coherent Light Source (LCLS) is the seventh and newest instrument at the world's first hard X-ray free-electron laser. It was designed with a primary focus on structural biology, employing the ultrafast pulses of X-rays from LCLS at atmospheric conditions to overcome radiation damage limitations in biological measurements. It is also capable of performing various time-resolved measurements. The MFX design consists of a versatile base system capable of supporting multiple methods, techniques and experimental endstations. The primary techniques supported are forward scattering and crystallography, with capabilities for various spectroscopic methods and time-resolved measurements. The location of the MFX instrument allows for utilization of multiplexing methods, increasing user access to LCLS by running multiple experiments simultaneously
Description:Date Completed 13.03.2019
Date Revised 21.05.2025
published: Print-Electronic
Citation Status PubMed-not-MEDLINE
ISSN:1600-5775
DOI:10.1107/S1600577519001577