pH-Responsive Zwitterionic Copolymer DHA-PBLG-PCB for Targeted Drug Delivery : A Computer Simulation Study

In this work, the self-assembled behaviors of zwitterionic copolymer docosahexaenoic acid- b-poly(γ-benzyl-l-glutamate)- b-poly(carboxybetaine methacrylate) (DHA-PBLG-PCB) and the loading and release mechanism of the anticancer drug doxorubicin (DOX) was investigated via computer simulations. The ef...

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Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 35(2019), 5 vom: 05. Feb., Seite 1944-1953
1. Verfasser: Hao, Lingxia (VerfasserIn)
Weitere Verfasser: Lin, Lin, Zhou, Jian
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2019
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antineoplastic Agents Drug Carriers Micelles Polymethacrylic Acids Polyglutamic Acid 25513-46-6 Doxorubicin 80168379AG