Sphingosine 1-Phosphate Receptor 1 Modulates CNTF-Induced Axonal Growth and Neuroprotection in the Mouse Visual System

The lack of axonal regeneration and neuronal cell death causes permanent neurological deficits in the injured CNS. Using the classical CNS injury model of optic nerve crush in mice, ciliary neurotrophic factor (CNTF) was found to stimulate retinal ganglion cell (RGC) survival and axonal growth, but...

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Détails bibliographiques
Publié dans:Neural plasticity. - 1998. - 2017(2017) vom: 19., Seite 6818970
Auteur principal: Joly, Sandrine (Auteur)
Autres auteurs: Dalkara, Deniz, Pernet, Vincent
Format: Article en ligne
Langue:English
Publié: 2017
Accès à la collection:Neural plasticity
Sujets:Journal Article Ciliary Neurotrophic Factor Neuroprotective Agents Receptors, Lysosphingolipid STAT3 Transcription Factor