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231225s2018 xx |||||o 00| ||eng c |
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|a 10.1111/jfd.12758
|2 doi
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|a pubmed25n0928.xml
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|a (NLM)29193152
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|a DE-627
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|c DE-627
|e rakwb
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| 041 |
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|a eng
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| 100 |
1 |
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|a Zhu, Z M
|e verfasserin
|4 aut
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| 245 |
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|a The high prevalence of pathogenic Vibrio harveyi with multiple antibiotic resistance in scale drop and muscle necrosis disease of the hybrid grouper, Epinephelus fuscoguttatus (♀) × E. lanceolatus (♂), in China
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| 264 |
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|c 2018
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|a Date Completed 17.08.2018
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|a Date Revised 30.09.2020
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2017 John Wiley & Sons Ltd.
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|a Scale drop and muscle necrosis disease with high mortality widely occurred recently in the hybrid grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂), a crucial cultured marine fish species in China. In this study, 30 Harveyi clade isolates of 27 Vibrio harveyi strains were isolated from diseased hybrid groupers in the south-east and north-east coastal areas of China. A total of 22 V. harveyi strains were determined to be pathogenic, and most challenged fish died within 2 days of infection; surviving individuals exhibited scale drop and deep dermal lesions as naturally diseased fish. Although five typical virulence genes, including luxR, toxRVh , chiA, serine protease and vhh widely existed in V. harveyi, no obvious correlation was established between virulent strains and virulence genes harboured in them. Furthermore, multiple antibiotic resistance was widely exhibited in Harveyi clade strains, particularly for penicillins, polypeptides, lincomycins, acetylspiramycin, streptomycin, metronidazole and bacitracin. And the multiple antibiotic resistance indices were gradually decreased from southern to northern areas of China. This study demonstrated that the pathogenic V. harveyi with multiple antibiotic resistance is highly prevalent in hybrid grouper in China, which requires particular attention
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|a Journal Article
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|a Vibrio harveyi
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| 650 |
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|a hybrid grouper
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| 650 |
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|a multiple antibiotic resistance
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| 650 |
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|a pathogenicity
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| 650 |
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|a Anti-Bacterial Agents
|2 NLM
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| 650 |
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|a DNA, Bacterial
|2 NLM
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| 650 |
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|a RNA, Ribosomal, 16S
|2 NLM
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| 700 |
1 |
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|a Dong, C F
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Weng, S P
|e verfasserin
|4 aut
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| 700 |
1 |
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|a He, J G
|e verfasserin
|4 aut
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| 773 |
0 |
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|i Enthalten in
|t Journal of fish diseases
|d 1998
|g 41(2018), 4 vom: 15. Apr., Seite 589-601
|w (DE-627)NLM098166034
|x 1365-2761
|7 nnas
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| 773 |
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|g volume:41
|g year:2018
|g number:4
|g day:15
|g month:04
|g pages:589-601
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|u http://dx.doi.org/10.1111/jfd.12758
|3 Volltext
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