A Case of Difficult-to-Diagnose Carcinomatous Meningitis Caused by Prostate Cancer Metastasis

A 66-year-old man was referred to our hospital because of right leg pain. Computed tomography (CT) revealed multiple osteolytic changes. His serum prostate-specific antigen (PSA) level was increased to 77.83 ng/ml at the time of hospitalization. A prostate biopsy was performed, and histological exam...

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Publié dans:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 62(2016), 5 vom: 05. Mai, Seite 265-9
Auteur principal: Shinohara, Masatake (Auteur)
Autres auteurs: Kiba, Keisuke, Yamada, Atsushi, Hatakeyama, Kinta, Mita, Yasunobu, Saka, Toshihisa, Hirao, Yoshihik
Format: Article
Langue:Japanese
Publié: 2016
Accès à la collection:Hinyokika kiyo. Acta urologica Japonica
Sujets:Case Reports English Abstract Journal Article
Description
Résumé:A 66-year-old man was referred to our hospital because of right leg pain. Computed tomography (CT) revealed multiple osteolytic changes. His serum prostate-specific antigen (PSA) level was increased to 77.83 ng/ml at the time of hospitalization. A prostate biopsy was performed, and histological examination results indicated poorly differentiated adenocarcinoma. Under the diagnosis of multiple bone metastasis of prostate cancer, androgen deprivation therapy was started. However, 1 month later, the patient was confused and lost appetite. Brain CT image demonstrated brain metastasis, and magnetic resonance image showed hydrocephalus. Although the patient underwent ventricular drainage because of a depressed level of consciousness, he died of primary disease complicated by pneumonia 3 months after the first visit. Perioperative cerebrospinal fluid cytological examination revealed adenocarcinoma cells. Therefore, a diagnosis of carcinomatous meningitis caused by prostate cancer metastasis was made
Description:Date Completed 29.08.2016
Date Revised 20.06.2016
published: Print
Citation Status MEDLINE
ISSN:0018-1994