Reversible Interactions of Proteins with Mixed Shell Polymeric Micelles : Tuning the Surface Hydrophobic/Hydrophilic Balance toward Efficient Artificial Chaperones

Molecular chaperones can elegantly fine-tune its hydrophobic/hydrophilic balance to assist a broad spectrum of nascent polypeptide chains to fold properly. Such precious property is difficult to be achieved by chaperone mimicking materials due to limited control of their surface characteristics that...

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Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 32(2016), 11 vom: 22. März, Seite 2737-49
Auteur principal: Wang, Jianzu (Auteur)
Autres auteurs: Song, Yiqing, Sun, Pingchuan, An, Yingli, Zhang, Zhenkun, Shi, Linqi
Format: Article en ligne
Langue:English
Publié: 2016
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, Non-U.S. Gov't Ethylene Glycols Micelles Polyesters Polymethacrylic Acids poly(2-methacryloyloxyethyl-phosphorylcholine) poly(epsilon-caprolactone)-b-poly(ethylene glycol) poly(epsilon-caprolactone)-block-poly(2-(methacryloyloxy)ethyl phosphorylcholine) Phosphorylcholine plus... 107-73-3 Carbonic Anhydrase I EC 4.2.1.-