Cardiac muscle organization revealed in 3-D by imaging whole-mount mouse hearts using two-photon fluorescence and confocal microscopy

The ability to image the entire adult mouse heart at high resolution in 3-D would provide enormous advantages in the study of heart disease. However, a technique for imaging nuclear/cellular detail as well as the overall structure of the entire heart in 3-D with minimal effort is lacking. To solve t...

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Détails bibliographiques
Publié dans:BioTechniques. - 1991. - 59(2015), 5 vom: 15. Nov., Seite 295-308
Auteur principal: Sivaguru, Mayandi (Auteur)
Autres auteurs: Fried, Glenn, Sivaguru, Barghav S, Sivaguru, Vignesh A, Lu, Xiaochen, Choi, Kyung Hwa, Saif, M Taher A, Lin, Brian, Sadayappan, Sakthivel
Format: Article en ligne
Langue:English
Publié: 2015
Accès à la collection:BioTechniques
Sujets:Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. MYBPC3 PAS labeling confocal microscopy heart failure heart-3-D two-photon whole-mount