Surveying the repair of ancient DNA from bones via high-throughput sequencing
DNA damage in the form of abasic sites, chemically altered nucleotides, and strand fragmentation is the foremost limitation in obtaining genetic information from many ancient samples. Upon cell death, DNA continues to endure various chemical attacks such as hydrolysis and oxidation, but repair pathw...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | BioTechniques. - 1993. - 59(2015), 1 vom: 22. Juli, Seite 19-25
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| 1. Verfasser: |
Mouttham, Nathalie
(VerfasserIn) |
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| Weitere Verfasser: |
Klunk, Jennifer,
Kuch, Melanie,
Fourney, Ron,
Poinar, Hendrik |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2015
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| Zugriff auf das übergeordnete Werk: | BioTechniques
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| Schlagworte: | Evaluation Study
Journal Article
Research Support, Non-U.S. Gov't
DNA damage
DNA repair
ancient DNA
high-throughput sequencing
DNA
9007-49-2
DNA Repair Enzymes
EC 6.5.1.- |
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