Parthenolide Relieves Pain and Promotes M2 Microglia/Macrophage Polarization in Rat Model of Neuropathy

Neuropathic pain treatment remains a challenge because pathomechanism is not fully understood. It is believed that glial activation and increased spinal nociceptive factors are crucial for neuropathy. We investigated the effect of parthenolide (PTL) on the chronic constriction injury to the sciatic...

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Détails bibliographiques
Publié dans:Neural plasticity. - 1998. - 2015(2015) vom: 01., Seite 676473
Auteur principal: Popiolek-Barczyk, Katarzyna (Auteur)
Autres auteurs: Kolosowska, Natalia, Piotrowska, Anna, Makuch, Wioletta, Rojewska, Ewelina, Jurga, Agnieszka M, Pilat, Dominika, Mika, Joanna
Format: Article en ligne
Langue:English
Publié: 2015
Accès à la collection:Neural plasticity
Sujets:Journal Article Research Support, Non-U.S. Gov't Analgesics Sesquiterpenes parthenolide 2RDB26I5ZB