Two-photon excitation of porphyrin-functionalized porous silicon nanoparticles for photodynamic therapy

Two-photon excitation of porphyrin-functionalized porous silicon nanoparticles for photodynamic therapy

© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 26(2014), 45 vom: 03. Dez., Seite 7643-8
1. Verfasser: Secret, Emilie (VerfasserIn)
Weitere Verfasser: Maynadier, Marie, Gallud, Audrey, Chaix, Arnaud, Bouffard, Elise, Gary-Bobo, Magali, Marcotte, Nathalie, Mongin, Olivier, El Cheikh, Khaled, Hugues, Vincent, Auffan, Mélanie, Frochot, Céline, Morère, Alain, Maillard, Philippe, Blanchard-Desce, Mireille, Sailor, Michael J, Garcia, Marcel, Durand, Jean-Olivier, Cunin, Frédérique
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. mannose nanoparticle photodynamic therapy porous silicon two-photon excitation Biocompatible Materials Photosensitizing Agents mehr... Porphyrins Mannose PHA4727WTP Silicon Z4152N8IUI
Beschreibung
Zusammenfassung:© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Porous silicon nanoparticles (pSiNPs) act as a sensitizer for the 2-photon excitation of a pendant porphyrin using NIR laser light, for imaging and photodynamic therapy. Mannose-functionalized pSiNPs can be vectorized to MCF-7 human breast cancer cells through a mannose receptor-mediated endocytosis mechanism to provide a 3-fold enhancement of the 2-photon PDT effect
Beschreibung:Date Completed 27.07.2015
Date Revised 30.09.2020
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201403415