Genetic Structure of and Evidence for Admixture between Western and Korean Native Pig Breeds Revealed by Single Nucleotide Polymorphisms

Comprehensive information on genetic diversity and introgression is desirable for the design of rational breed improvement and conservation programs. Despite the concerns regarding the genetic introgression of Western pig breeds into the gene pool of the Korean native pig (KNP), the level of this ad...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Asian-Australasian journal of animal sciences. - 1998. - 27(2014), 9 vom: 02. Sept., Seite 1263-9
1. Verfasser: Edea, Zewdu (VerfasserIn)
Weitere Verfasser: Kim, Sang-Wook, Lee, Kyung-Tai, Kim, Tae Hun, Kim, Kwan-Suk
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Asian-Australasian journal of animal sciences
Schlagworte:Journal Article Admixture Genetic Diversity Korean Native Pig Single Nucleotide Polymorphism
LEADER 01000caa a22002652 4500
001 NLM241496098
003 DE-627
005 20250217105807.0
007 cr uuu---uuuuu
008 231224s2014 xx |||||o 00| ||eng c
024 7 |a 10.5713/ajas.2014.14096  |2 doi 
028 5 2 |a pubmed25n0804.xml 
035 |a (DE-627)NLM241496098 
035 |a (NLM)25178369 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Edea, Zewdu  |e verfasserin  |4 aut 
245 1 0 |a Genetic Structure of and Evidence for Admixture between Western and Korean Native Pig Breeds Revealed by Single Nucleotide Polymorphisms 
264 1 |c 2014 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Completed 02.09.2014 
500 |a Date Revised 21.10.2021 
500 |a published: Print 
500 |a Citation Status PubMed-not-MEDLINE 
520 |a Comprehensive information on genetic diversity and introgression is desirable for the design of rational breed improvement and conservation programs. Despite the concerns regarding the genetic introgression of Western pig breeds into the gene pool of the Korean native pig (KNP), the level of this admixture has not yet been quantified. In the present study, we genotyped 93 animals, representing four Western pig breeds and KNP, using the porcine SNP 60K BeadChip to assess their genetic diversity and to estimate the level of admixture among the breeds. Expected heterozygosity was the lowest in Berkshire (0.31) and highest in Landrace (0.42). Population differentiation (FST) estimates were significantly different (p<0.000), accounting for 27% of the variability among the breeds. The evidence of inbreeding observed in KNP (0.029) and Yorkshire (0.031) may result in deficient heterozygosity. Principal components one (PC1) and two (PC2) explained approximately 35.06% and 25.20% of the variation, respectively, and placed KNP somewhat proximal to the Western pig breeds (Berkshire and Landrace). When K = 2, KNP shared a substantial proportion of ancestry with Western breeds. Similarly, when K = 3, over 86% of the KNP individuals were in the same cluster with Berkshire and Landrace. The linkage disquilbrium (LD) values at r (2) 0.3, the physical distance at which LD decays below a threshold of 0.3, ranged from 72.40 kb in Landrace to 85.86 kb in Yorkshire. Based on our structure analysis, a substantial level of admixture between Western and Korean native pig breeds was observed 
650 4 |a Journal Article 
650 4 |a Admixture 
650 4 |a Genetic Diversity 
650 4 |a Korean Native Pig 
650 4 |a Single Nucleotide Polymorphism 
700 1 |a Kim, Sang-Wook  |e verfasserin  |4 aut 
700 1 |a Lee, Kyung-Tai  |e verfasserin  |4 aut 
700 1 |a Kim, Tae Hun  |e verfasserin  |4 aut 
700 1 |a Kim, Kwan-Suk  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Asian-Australasian journal of animal sciences  |d 1998  |g 27(2014), 9 vom: 02. Sept., Seite 1263-9  |w (DE-627)NLM098195883  |x 1011-2367  |7 nnns 
773 1 8 |g volume:27  |g year:2014  |g number:9  |g day:02  |g month:09  |g pages:1263-9 
856 4 0 |u http://dx.doi.org/10.5713/ajas.2014.14096  |3 Volltext 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_350 
951 |a AR 
952 |d 27  |j 2014  |e 9  |b 02  |c 09  |h 1263-9