A case of effective neoadjuvant chemotherapy (MVEC) against right ureteral cancer involving bladder (cT4N1M0)
Poorly differentiated ureteral cancer has a poor prognosis, and tumor recurrence is frequent even after nephroureterectomy. We performed neoadjuvant chemotherapy to prevent postoperative recurrence. A 74-year-old man was diagnosed with ureteral cancer (3 cm) by magnetic resonance imaging (MRI). The...
| Publié dans: | Hinyokika kiyo. Acta urologica Japonica. - 1962. - 60(2014), 4 vom: 30. Apr., Seite 179-82 |
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| Auteur principal: | |
| Autres auteurs: | , , , , |
| Format: | Article |
| Langue: | Japanese |
| Publié: |
2014
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| Accès à la collection: | Hinyokika kiyo. Acta urologica Japonica |
| Sujets: | Case Reports English Abstract Journal Article Antibiotics, Antineoplastic Antimetabolites, Antineoplastic Antineoplastic Agents Antineoplastic Agents, Phytogenic Epirubicin 3Z8479ZZ5X Vinblastine plus... |
| Résumé: | Poorly differentiated ureteral cancer has a poor prognosis, and tumor recurrence is frequent even after nephroureterectomy. We performed neoadjuvant chemotherapy to prevent postoperative recurrence. A 74-year-old man was diagnosed with ureteral cancer (3 cm) by magnetic resonance imaging (MRI). The clinical stage was T4N1M0. Histological examination by transurethral biopsy revealed an urothelial carcinoma, G3, pT1. After a month, the tumor size increased from 3.0 cm to 4.0 cm. With two cycles of neoadjuvant chemotherapy consisting of methotrexate, vinblastine, epirubicin and cisplatin (MVEC) partial remission (regression rate : 87%) was achieved, Following MVEC, right retroperitoneoscopy-assisted nephroureterectomy, total cystectomy, and ileal conduit were performed. Pathological stage was pT0. After two years, postoperative recurrence has not appeared |
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| Description: | Date Completed 12.08.2014 Date Revised 02.06.2014 published: Print Citation Status MEDLINE |
| ISSN: | 0018-1994 |