Functionalized mesoporous silica nanoparticles with mucoadhesive and sustained drug release properties for potential bladder cancer therapy

The synthesis of a series of β-cyclodextrin modified mesoporous silica nanoparticles with hydroxyl, amino, and thiol groups was described. A comparison of their mucoadhesive properties and potential as a drug delivery system for superficial bladder cancer therapy was made. The thiol-functionalized n...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 30(2014), 21 vom: 03. Juni, Seite 6151-61
1. Verfasser: Zhang, Quan (VerfasserIn)
Weitere Verfasser: Neoh, Koon Gee, Xu, Liqun, Lu, Shengjie, Kang, En Tang, Mahendran, Ratha, Chiong, Edmund
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antineoplastic Agents Disulfides Sulfhydryl Compounds Silicon Dioxide 7631-86-9 Doxorubicin 80168379AG Fluorescein-5-isothiocyanate mehr... I223NX31W9 Cysteine K848JZ4886