Ultrathin hybrid films of polyoxohydroxy clusters and proteins layer-by-layer assembly and their optical and mechanical properties

Ultrathin hybrid films of polyoxohydroxy clusters and proteins : layer-by-layer assembly and their optical and mechanical properties

The hierarchical assembly of inorganic and organic building blocks is an efficient strategy to produce high-performance materials which has been demonstrated in various biomaterials. Here, we report a layer-by-layer (LBL) assembly method to fabricate ultrathin hybrid films from nanometer-scale ionic...

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Détails bibliographiques
Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 30(2014), 18 vom: 13. Mai, Seite 5248-55
Auteur principal: Yan, You-Xian (Auteur)
Autres auteurs: Yao, Hong-Bin, Smart, Scott E, Mao, Li-Bo, Hu, Wei, Yuan, Shaotang, Du-Thumm, Laurence, Masters, James G, Yu, Shu-Hong, Pan, Long
Format: Article en ligne
Langue:English
Publié: 2014
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, Non-U.S. Gov't Biocompatible Materials Polymers Serum Albumin, Bovine 27432CM55Q
Description
Résumé:The hierarchical assembly of inorganic and organic building blocks is an efficient strategy to produce high-performance materials which has been demonstrated in various biomaterials. Here, we report a layer-by-layer (LBL) assembly method to fabricate ultrathin hybrid films from nanometer-scale ionic clusters and proteins. Two types of cationic clusters (hydrolyzed aluminum clusters and zirconium-glycine clusters) were assembled with negatively charged bovine serum albumin (BSA) protein to form high-quality hybrid films, due to their strong electrostatic interactions and hydrogen bonding. The obtained hybrid films were characterized by scanning electron microscope (SEM), UV-vis, Raman spectroscopy, Fourier transform infrared spectroscopy (FTIR), X-ray fluorescence (XRF), and X-ray diffraction (XRD). The results demonstrated that the cluster-protein hybrid films exhibited structural homogeneity, relative transparency, and bright blue fluorescence. More importantly, these hybrid films displayed up to a 70% increase in hardness and up to a 100% increase in reduced Young's modulus compared to the pure BSA film. These hybrid cluster-protein films could be potentially used as biomedical coatings in the future because of their good transparency and excellent mechanical properties
Description:Date Completed 15.04.2015
Date Revised 16.11.2017
published: Print-Electronic
Citation Status MEDLINE
ISSN:1520-5827
DOI:10.1021/la500434a