Renewal of the air-water interface as a critical system parameter of protein stability : aggregation of the human growth hormone and its prevention by surface-active compounds
Soluble proteins are often highly unstable under mixing conditions that involve dynamic contacting between the main liquid phase and a gas phase. The recombinant human growth hormone (rhGH) was recently shown to undergo aggregation into micrometer-sized solid particles composed of non-native (mis- o...
| Publié dans: | Langmuir : the ACS journal of surfaces and colloids. - 1985. - 29(2013), 49 vom: 10. Dez., Seite 15240-50 |
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| Auteur principal: | |
| Autres auteurs: | , |
| Format: | Article en ligne |
| Langue: | English |
| Publié: |
2013
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| Accès à la collection: | Langmuir : the ACS journal of surfaces and colloids |
| Sujets: | Journal Article Research Support, Non-U.S. Gov't Surface-Active Agents Water 059QF0KO0R Poloxamer 106392-12-5 Human Growth Hormone 12629-01-5 |
| Accès en ligne |
Volltext |