Theory of effective drug release from medical implants based on the Higuchi model and physico-chemical hydrodynamics
Combining the approach of colloid transport with the generalized Higuchi theory of drug release and with the concept of minimum inhibitory concentration (MIC) known in microbiology, the theory of effective drug release from implants has been developed. Effective release of an antibiotic at a concent...
| Publié dans: | Colloids and surfaces. A, Physicochemical and engineering aspects. - 1999. - 409(2012) vom: 05. Sept., Seite 10-20 |
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| Format: | Article |
| Langue: | English |
| Publié: |
2012
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| Accès à la collection: | Colloids and surfaces. A, Physicochemical and engineering aspects |
| Sujets: | Journal Article Antibiotic-loaded catheter Catheter Controlled drug release Convective diffusion Diffusion layer thickness Diffusivity within tissue Effective drug release IES Incision exit site plus... |