Surfaces that sequester serum-borne heparin amplify growth factor activity

Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Détails bibliographiques
Publié dans:Advanced materials (Deerfield Beach, Fla.). - 1998. - 23(2011), 45 vom: 01. Dez., Seite 5415-8
Auteur principal: Hudalla, Gregory A (Auteur)
Autres auteurs: Koepsel, Justin T, Murphy, William L
Format: Article en ligne
Langue:English
Publié: 2011
Accès à la collection:Advanced materials (Deerfield Beach, Fla.)
Sujets:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Peptide Fragments Fibroblast Growth Factor 2 103107-01-3 Polyethylene Glycols 3WJQ0SDW1A Heparin 9005-49-6
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520 |a Surfaces presenting a heparin-binding peptide can non-covalently sequester heparin from culture supplements, such as fetal bovine serum. In turn, sequestered, serum-borne heparin can non-covalently localize growth factors at the cell-material interface, resulting in amplified growth factor bioactivity 
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