Chitosan-g-MPEG-modified alginate/chitosan hydrogel microcapsules : a quantitative study of the effect of polymer architecture on the resistance to protein adsorption

The chemical modification of the alginate/chitosan/alginate (ACA) hydrogel microcapsule with methoxy poly(ethylene glycol) (MPEG) was investigated to reduce nonspecific protein adsorption and improve biocompatibility in vivo. The graft copolymer chitosan-g-MPEG (CS-g-MPEG) was synthesized, and then...

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Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 26(2010), 22 vom: 16. Nov., Seite 17156-64
Auteur principal: Zheng, Jia N (Auteur)
Autres auteurs: Xie, Hong G, Yu, Wei T, Liu, Xiu D, Xie, Wei Y, Zhu, Jing, Ma, Xiao J
Format: Article en ligne
Langue:English
Publié: 2010
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, Non-U.S. Gov't Aldehydes Alginates Capsules Hexuronic Acids Hydrogels Immunoglobulin G methoxy poly(ethylene glycol)-grafted chitosan Polyethylene Glycols plus... 3WJQ0SDW1A Glucuronic Acid 8A5D83Q4RW Chitosan 9012-76-4