A role for autoantibodies in enhancement of pro-inflammatory cytokine responses to a self-antigen, thyroid peroxidase

The role of thyroid peroxidase (TPO) antibodies (TPOAbs) in the pathogenesis of autoimmune thyroid disease is unclear. We selected sera with a high concentration of TPOAbs from eleven patients with Hashimoto's thyroiditis (HT), ten healthy monozygotic co-twins to HT patients, and twelve healthy...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 133(2009), 2 vom: 15. Nov., Seite 218-27
1. Verfasser: Nielsen, Claus H (VerfasserIn)
Weitere Verfasser: Brix, Thomas H, Leslie, R Graham Q, Hegedüs, Laszlo
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antibodies Autoantibodies Autoantigens Cytokines IL10 protein, human IL4 protein, human IL6 protein, human Immune Sera mehr... Immunoglobulin G Interleukin-6 Receptors, IgG Tetanus Toxoid Tumor Necrosis Factor-alpha Interleukin-10 130068-27-8 Interleukin-4 207137-56-2 Interferon-gamma 82115-62-6 Iodide Peroxidase EC 1.11.1.8