Disruption of Nrf2 enhances susceptibility to airway inflammatory responses induced by low-dose diesel exhaust particles in mice

To test our hypothesis that diesel exhaust particle (DEP)-induced oxidative stress and host antioxidant responses play a key role in the development of DEP-induced airway inflammatory diseases, C57BL/6 nuclear erythroid 2 P45-related factor 2 (Nrf2) knockout (Nrf2(-/-)) and wild-type mice were expos...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 128(2008), 3 vom: 01. Sept., Seite 366-73
1. Verfasser: Li, Ying Ji (VerfasserIn)
Weitere Verfasser: Takizawa, Hajime, Azuma, Arata, Kohyama, Tadashi, Yamauchi, Yasuhiro, Takahashi, Satoru, Yamamoto, Masayuki, Kawada, Tomoyuki, Kudoh, Shoji, Sugawara, Isamu
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antioxidants Cytokines Immunoglobulin G NF-E2-Related Factor 2 Vehicle Emissions Immunoglobulin E 37341-29-0