P38 mitogen-activated protein kinase mediates glucocorticoid receptor function induced by dexamethasone in acute lymphoblastic leukemia cells
OBJECTIVE: Glucocorticoid (GC) has occupied a central role in the treatment of acute lymphoblastic leukemia due to its ability to induce apoptosis in neoplastic lymphoid cells. Glucocorticoid resistance is present among 20% initial acute lymphoblastic leukemia, even 80% refractory acute lymphoblasti...
| Publié dans: | Zhonghua er ke za zhi = Chinese journal of pediatrics. - 1960. - 45(2007), 9 vom: 19. Sept., Seite 687-91 |
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| Auteur principal: | |
| Autres auteurs: | , , |
| Format: | Article |
| Langue: | Chinese |
| Publié: |
2007
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| Accès à la collection: | Zhonghua er ke za zhi = Chinese journal of pediatrics |
| Sujets: | Journal Article Enzyme Inhibitors Glucocorticoids Imidazoles NR3C1 protein, human Pyridines Receptors, Glucocorticoid Dexamethasone 7S5I7G3JQL Protein Serine-Threonine Kinases plus... |