Identification of insulin autoantibodies of IgA isotype that preferentially target non-human insulin

Insulin autoantibodies (IAA) precede clinical type 1 diabetes in children. Immunization events leading to IAA are unknown. The aim of this study was to determine whether some IAA result from mucosal immunization. IgA-IAA and binding of IAA to non-human insulin were examined in selected high and low...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 124(2007), 1 vom: 15. Juli, Seite 77-82
1. Verfasser: Koczwara, Kerstin (VerfasserIn)
Weitere Verfasser: Muller, Daniela, Achenbach, Peter, Ziegler, Anette-G, Bonifacio, Ezio
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Autoantibodies Immunoglobulin A Immunoglobulin G Insulin Insulin Antibodies