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231223s2006 xx ||||| 00| ||eng c |
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|a eng
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1 |
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|a Johns, Jennifer L
|e verfasserin
|4 aut
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|a Lymph node aspirate from a California wine-country dog
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|c 2006
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|a Text
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|a ohne Hilfsmittel zu benutzen
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|2 rdamedia
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|2 rdacarrier
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|a Date Completed 08.08.2006
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|a Date Revised 10.11.2019
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|a published: Print
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|a Citation Status MEDLINE
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|a A 4-year-old, male Golden Retriever was presented to the Veterinary Medical Teaching Hospital at the University of California-Davis with a history of lethargy, inappetance, and vomiting. The patient had generalized lymphadenomegaly, marked thrombocytopenia, mild anemia, and moderate hypoalbuminemia. Moderate to marked histiocytic inflammation and lymphocytic-plasmacytic reactivity of the mesenteric, left popliteal, and right mandibular lymph nodes were diagnosed cytologically. Many macrophages contained granular to amorphous material of a uniform blue color, occasionally in morula formation, suggestive of rickettsial organisms. Exposure to raw trout was subsequently documented, leading to a presumptive diagnosis of salmon poisoning disease (SPD). The patient responded quickly to doxycycline therapy for the causative agent of SPD (Neorickettsia helminthoeca). SPD should be considered as a differential diagnosis for a canine patient with clinical signs of vomiting, diarrhea, lethargy, and lymphadenomegaly; laboratory findings of thrombocytopenia and hypoalbuminemia; and potential exposure to raw fish from an endemic area. The cytologic finding of rickettsial inclusions within lymph node macrophages is reportedly seen within a majority of SPD cases and can be valuable in supporting a clinical suspicion of SPD, as it was in this case
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|a Case Reports
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|a Journal Article
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|a Anti-Bacterial Agents
|2 NLM
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|a Doxycycline
|2 NLM
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|a N12000U13O
|2 NLM
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|a Strasser, Jennifer L
|e verfasserin
|4 aut
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|a Zinkl, Joseph G
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|4 aut
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|a Christopher, Mary M
|e verfasserin
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|i Enthalten in
|t Veterinary clinical pathology
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|g 35(2006), 2 vom: 16. Juni, Seite 243-6
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|g volume:35
|g year:2006
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|g day:16
|g month:06
|g pages:243-6
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