Modulation of the systemic inflammatory response by recombinant human interleukin-11 : a prospective randomized placebo controlled clinical study in patients with hematological malignancy

The immunomodulatory activities of recombinant human interleukin-11 (rhIL-11) were investigated in a clinical trial among patients with hematological malignancy, randomized to either rhIL-11 or placebo throughout chemotherapy. Daily serum concentrations of sTNFRI, IL-6, IL-8, TNFalpha, and CRP were...

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Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 120(2006), 2 vom: 15. Aug., Seite 129-37
Auteur principal: Ellis, Michael (Auteur)
Autres auteurs: Hedstrom, Ulla, Frampton, Chris, Alizadeh, Hussain, Kristensen, Jorgen, Shammas, Fuad V, al-Ramadi, Basel K
Format: Article
Langue:English
Publié: 2006
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Clinical Trial Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't Anti-Inflammatory Agents Biomarkers IL11 protein, human Interleukin-11 Interleukin-6 Interleukin-8 plus... Receptors, Tumor Necrosis Factor, Type I Recombinant Proteins Tumor Necrosis Factor-alpha C-Reactive Protein 9007-41-4