T-cell epitopes of the La/SSB autoantigen prediction based on the homology modeling of HLA-DQ2/DQ7 with the insulin-B peptide/HLA-DQ8 complex

T-cell epitopes of the La/SSB autoantigen : prediction based on the homology modeling of HLA-DQ2/DQ7 with the insulin-B peptide/HLA-DQ8 complex

T-cell epitopes are important components of the inappropriate response of the immune system to self-proteins in autoimmune diseases. In this study, the candidate T-cell epitopes of the La/SSB autoantigen, the main target of the autoimmune response in patients with Sjogren's Syndrome (SS), and S...

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Bibliographische Detailangaben
Veröffentlicht in:Journal of computational chemistry. - 1984. - 27(2006), 9 vom: 15. Juli, Seite 1033-44
1. Verfasser: Kosmopoulou, Aggeliki (VerfasserIn)
Weitere Verfasser: Vlassi, Metaxia, Stavrakoudis, Athanassios, Sakarellos, Constantinos, Sakarellos-Daitsiotis, Maria
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Journal of computational chemistry
Schlagworte:Journal Article Autoantigens Epitopes, T-Lymphocyte HLA-DQ Antigens Insulin Peptide Fragments Ribonucleoproteins