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|a DE-627
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|a jpn
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|a Hoshi, Akio
|e verfasserin
|4 aut
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|a BK virus nephropathy in a kidney transplant recipient
|b a case report and literature review
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|c 2006
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|a Text
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|a Date Completed 24.03.2006
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|a Date Revised 15.11.2006
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|a published: Print
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|a Citation Status MEDLINE
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|a BK virus nephropathy (BKVN) has emerged as an important cause of allograft dysfunction and loss in kidney transplant recipients. We present a case in a 30-year-old female who underwent ABO-compatible living kidney transplant from her mother and was maintained with tacrolimus, mycophenolate mofetil and prednisolone. The serum creatinine level was stabilized about 0.9 mg/dl on postoperative day (POD) 35. On POD258, the serum creatinine increased to 1.8 mg/dl and the patient received methylpredonisolone pulse therapy under the diagnosis of acute rejection, which resulted in further increase in creatinine level from 1.8 to 2.6 mg/dl. Urine cytology showed decoy cells, but renal biopsy specimen showed no evidence of viral infection. Despite histopathological findings, positive urine and serum BKV-DNA suggested that allograft dysfunction was caused by BKVN. Therefore, the immunosuppession was reduced and gamma-globuline was given for 2 weeks. After the treatment, urine cytology became negative for decoy cells and serum creatinine level recovered to 2.0 mg/dl. On POD456, serum creatinine level was stabilized about 1.8 mg/dl and decoy cells remained negative
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|a Case Reports
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|a English Abstract
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|a Journal Article
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|a DNA, Viral
|2 NLM
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|a Segawa, Takehiko
|e verfasserin
|4 aut
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|a Takahashi, Takeshi
|e verfasserin
|4 aut
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|a Nakamura, Eijiro
|e verfasserin
|4 aut
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|a Higashi, Shin
|e verfasserin
|4 aut
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|a Ito, Noriyuki
|e verfasserin
|4 aut
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|a Yamamoto, Shingo
|e verfasserin
|4 aut
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|a Kamoto, Toshiyuki
|e verfasserin
|4 aut
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|a Ogawa, Osamu
|e verfasserin
|4 aut
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|i Enthalten in
|t Hinyokika kiyo. Acta urologica Japonica
|d 1962
|g 52(2006), 2 vom: 01. Feb., Seite 119-23
|w (DE-627)NLM012631779
|x 0018-1994
|7 nnns
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|g volume:52
|g year:2006
|g number:2
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|g pages:119-23
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