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20250207000330.0 |
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231223s2006 xx ||||| 00| ||eng c |
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|a pubmed25n0533.xml
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|a (DE-627)NLM159864836
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|a (NLM)16386957
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a eng
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| 100 |
1 |
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|a Gallot, Géraldine
|e verfasserin
|4 aut
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| 245 |
1 |
2 |
|a T cell repertoire and Epstein-Barr virus-specific T cell response in chronic active Epstein-Barr virus infection
|b a case study
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| 264 |
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1 |
|c 2006
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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| 500 |
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|a Date Completed 17.04.2006
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| 500 |
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|a Date Revised 10.12.2019
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| 500 |
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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| 520 |
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|a In a patient with chronic active Epstein-Barr virus infection associated with vasculitis and fulminant CD4+ T cell lymphoproliferative disorder, we probed the peripheral blood mononuclear cells (PBMC) for the presence of an EBV-specific T cell repertoire and tested the possible relationship between the lymphocytic infiltrate and the EBV-specific T cell response. Our results give credence to the presence of an apparently normal EBV-specific memory T cell response after in vitro reactivation of the patient's PBMC with autologous infected B lymphoblastoid cell lines. In keeping with the characterization of the vasculitis, certain T cell subsets were detected after expansion of skin lesion-infiltrating lymphocytes and were found to be infected with EBV. These particular T cell expansions were neither the effectors nor the targets of the in vitro reactivated EBV-specific T cells, thus excluding a simple relationship between EBV, the skin lesions, and the T cell expansions frequently observed in these patients
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| 650 |
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4 |
|a Case Reports
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| 650 |
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4 |
|a Journal Article
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| 650 |
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4 |
|a Research Support, Non-U.S. Gov't
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| 650 |
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7 |
|a Complementarity Determining Regions
|2 NLM
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| 650 |
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7 |
|a DNA, Viral
|2 NLM
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| 650 |
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7 |
|a Epitopes, T-Lymphocyte
|2 NLM
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| 650 |
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7 |
|a Peptide Fragments
|2 NLM
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| 650 |
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7 |
|a Receptors, Antigen, T-Cell, alpha-beta
|2 NLM
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| 650 |
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7 |
|a Tumor Necrosis Factor-alpha
|2 NLM
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| 650 |
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7 |
|a Viral Proteins
|2 NLM
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| 700 |
1 |
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|a Hamidou, Mohamed A
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Clémenceau, Béatrice
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Gaschet, Joëlle
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Tiberghien, Pierre
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Ferrand, Christophe
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Vivien, Régine
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Barbarot, Sébastien
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Coste-Burel, Marianne
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Moreau, Anne
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Vié, Henri
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Clinical immunology (Orlando, Fla.)
|d 1999
|g 119(2006), 1 vom: 15. Apr., Seite 79-86
|w (DE-627)NLM098196855
|x 1521-6616
|7 nnns
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| 773 |
1 |
8 |
|g volume:119
|g year:2006
|g number:1
|g day:15
|g month:04
|g pages:79-86
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| 912 |
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|a GBV_USEFLAG_A
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| 912 |
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|a SYSFLAG_A
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| 912 |
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|a GBV_NLM
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| 912 |
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|a GBV_ILN_11
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| 912 |
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|a GBV_ILN_24
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| 912 |
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|a GBV_ILN_350
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| 951 |
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|a AR
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| 952 |
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|d 119
|j 2006
|e 1
|b 15
|c 04
|h 79-86
|