High-throughput site-directed mutagenesis using oligonucleotides synthesized on DNA chips

Site-directed mutagenesis has greatly helped researchers both to understand the precise role of specific residues in coding sequences and to generate variants of proteins that have acquired new characteristics. Today's demands for more complete functional cartographies of proteins and advances...

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Publié dans:BioTechniques. - 1991. - 39(2005), 3 vom: 14. Sept., Seite 363-8
Auteur principal: Saboulard, Didier (Auteur)
Autres auteurs: Dugas, Vincent, Jaber, Mehdi, Broutin, Jérôme, Souteyrand, Eliane, Sylvestre, Julien, Delcourt, Marc
Format: Article
Langue:English
Publié: 2005
Accès à la collection:BioTechniques
Sujets:Evaluation Study Journal Article Technical Report Interleukin-15 Oligonucleotides