Humoral autoimmune responses to glutamic acid decarboxylase have similar target epitopes and subclass that show titer-dependent disease association

Humoral autoimmune responses to glutamic acid decarboxylase have similar target epitopes and subclass that show titer-dependent disease association

Glutamic acid decarboxylase (GAD) is an autoantigen in stiff man syndrome (SMS) and type 1 diabetes (T1DM). Different GAD autoantibody characteristics in these disorders have suggested distinct underlying mechanisms of autoimmunity. Here, it is shown that increased prevalence of autoantibodies to GA...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 117(2005), 1 vom: 01. Okt., Seite 31-5
1. Verfasser: Piquer, Sandra (VerfasserIn)
Weitere Verfasser: Belloni, Cristina, Lampasona, Vito, Bazzigaluppi, Elena, Vianello, Marika, Giometto, Bruno, Bosi, Emanuele, Bottazzo, Gian Franco, Bonifacio, Ezio
Format: Aufsatz
Sprache:English
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Comparative Study Journal Article Autoantibodies Epitopes, B-Lymphocyte Glutamate Decarboxylase EC 4.1.1.15