Layer by layer self-assembled polyelectrolyte multilayers with embedded phospholipid vesicles

We describe a method to embed phospholipid vesicles into polyelectrolyte multilayers built up by the alternate deposition of polyanions and polycations. Before deposition, the vesicles are rigidified by polycation adsorption onto their surface avoiding their fusion once deposited on the multilayer s...

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Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1991. - 20(2004), 12 vom: 08. Juni, Seite 4835-9
1. Verfasser: Michel, Marc (VerfasserIn)
Weitere Verfasser: Vautier, Dominique, Voegel, Jean-Claude, Schaaf, Pierre, Ball, Vincent
Format: Aufsatz
Sprache:English
Veröffentlicht: 2004
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Imines Liposomes Phospholipids Polyamines Polyethylenes poly(ethylene imine) Polyglycolic Acid 26009-03-0 polyallylamine 30551-89-4
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245 1 0 |a Layer by layer self-assembled polyelectrolyte multilayers with embedded phospholipid vesicles 
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520 |a We describe a method to embed phospholipid vesicles into polyelectrolyte multilayers built up by the alternate deposition of polyanions and polycations. Before deposition, the vesicles are rigidified by polycation adsorption onto their surface avoiding their fusion once deposited on the multilayer surface. The vesicles adsorb to form a compact and "hard" monolayer as imaged by atomic force microscopy. The thickness of the adsorbed vesicle layer, of the order of 250 nm, is very close to the diameter of the vesicles in solution. This work should open the route to the buildup of multilayer films containing phospholipid vesicles that could act as "reservoirs" for drugs or enzymatic nanoreactors 
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650 7 |a Liposomes  |2 NLM 
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700 1 |a Vautier, Dominique  |e verfasserin  |4 aut 
700 1 |a Voegel, Jean-Claude  |e verfasserin  |4 aut 
700 1 |a Schaaf, Pierre  |e verfasserin  |4 aut 
700 1 |a Ball, Vincent  |e verfasserin  |4 aut 
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