Characterization of in vivo expanded OspA-specific human T-cell clones

Characterization of in vivo expanded OspA-specific human T-cell clones

A panel of CD4 T-cell clones was isolated from synovial fluid by single cell flow cytometry from a patient with treatment-resistant Lyme arthritis using a DRB1*0401 major histocompatibility complex (MHC) class II tetramer covalently loaded with outer surface protein A (OspA) peptide164-175, an immun...

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Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 115(2005), 3 vom: 31. Juni, Seite 313-22
Auteur principal: Ausubel, Lara J (Auteur)
Autres auteurs: O'Connor, Kevin C, Baecher-Allen, Clare, Trollmo, Christina, Kessler, Benedikt, Hekking, Brian, Merritt, David, Meyer, Abbie L, Kwok, Bill, Ploegh, Hidde, Huber, Brigitte T, Hafler, David A
Format: Article
Langue:English
Publié: 2005
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Antigens, Surface Bacterial Outer Membrane Proteins Bacterial Vaccines HLA-DR Antigens HLA-DRB1 Chains HLA-DRB1*04:01 antigen plus... Lipoproteins OspA protein Peptide Fragments Receptors, Antigen, T-Cell