Molecular dynamics simulation of clustered DNA damage sites containing 8-oxoguanine and abasic site

Molecular dynamics simulation of clustered DNA damage sites containing 8-oxoguanine and abasic site

Clustered DNA damage sites induced by ionizing radiation have been suggested to have serious consequences to organisms, such as cancer, due to their reduced probability to be repaired by the enzymatic repair machinery of the cell. Although experimental results have revealed that clustered DNA damage...

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Bibliographische Detailangaben
Veröffentlicht in:Journal of computational chemistry. - 1984. - 26(2005), 8 vom: 15. Juni, Seite 788-98
1. Verfasser: Fujimoto, Hirofumi (VerfasserIn)
Weitere Verfasser: Pinak, Miroslav, Nemoto, Toshiyuki, O'Neill, Peter, Kume, Etsuo, Saito, Kimiaki, Maekawa, Hideaki
Format: Aufsatz
Sprache:English
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Journal of computational chemistry
Schlagworte:Journal Article Polynucleotides apyrimidinic acid Apurinic Acid 11002-22-5 Guanosine 12133JR80S 8-hydroxyguanosine 3868-31-3