Investigation of zinc-containing peptide deformylase from Leptospira interrogans by X-ray absorption near-edge spectroscopy

Investigation of zinc-containing peptide deformylase from Leptospira interrogans by X-ray absorption near-edge spectroscopy

Peptide deformylase (PDF, EC 3.5.1.27) is essential for the normal growth of eubacterium but not for mammalians. Recently, PDF has been studied as a target for new antibiotics. Its activity is strongly dependent on the bound metal ion. The crystallographic studies did not show any significant struct...

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Veröffentlicht in:Journal of synchrotron radiation. - 1994. - 12(2005), Pt 1 vom: 23. Jan., Seite 111-4
1. Verfasser: Li, Shujun (VerfasserIn)
Weitere Verfasser: Zhou, Zhaocai, Chu, Wangsheng, Gong, Weimin, Benfatto, Maurizio, Hu, Tiandou, Xie, Yaning, Xian, Dingchang, Wu, Ziyu
Format: Aufsatz
Sprache:English
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Journal of synchrotron radiation
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Amidohydrolases EC 3.5.- peptide deformylase EC 3.5.1.88 Zinc J41CSQ7QDS