The tetraspan protein EMP2 increases surface expression of class I major histocompatibility complex proteins and susceptibility to CTL-mediated cell death

Dysregulation of class I major histocompatibility (MHC1) expression is an important mechanism of immunologic resistance for certain virus-infected or neoplastic cells. This study characterizes a new molecule affecting MHC1 expression and CTL cytotoxicity. Epithelial membrane protein 2 (EMP2) is a te...

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Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 107(2003), 2 vom: 30. Mai, Seite 129-36
Auteur principal: Wadehra, Madhuri (Auteur)
Autres auteurs: Su, Helen, Gordon, Lynn K, Goodglick, Lee, Braun, Jonathan
Format: Article
Langue:English
Publié: 2003
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Emp2 protein, mouse Histocompatibility Antigens Class I Lymphocyte Function-Associated Antigen-1 Membrane Glycoproteins Intercellular Adhesion Molecule-1 126547-89-5 G(M1) Ganglioside 37758-47-7