The immune modulator FYT720 prevents autoimmune diabetes in nonobese diabetic mice

FTY720 is a novel immune regulatory drug derived from the fungal sphingosine analog ISP-1 (myriocin). FTY720 causes a redistribution of lymphocytes from circulation to secondary lymphoid tissues. Type 1 diabetes is an autoimmune disorder caused by cellular-mediated destruction of insulin-producing p...

Description complète

Détails bibliographiques
Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 107(2003), 1 vom: 01. Apr., Seite 30-5
Auteur principal: Yang, Zandong (Auteur)
Autres auteurs: Chen, Meng, Fialkow, Lawrence B, Ellett, Justin D, Wu, Runpei, Brinkmann, Volker, Nadler, Jerry L, Lynch, Kevin R
Format: Article
Langue:English
Publié: 2003
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Immunosuppressive Agents Insulin Propylene Glycols Fingolimod Hydrochloride G926EC510T Glucose IY9XDZ35W2 plus... Sphingosine NGZ37HRE42